Depression Management Hints and Tips

If you’re struggling with depression, tune in for a great discussion — from two people who have been there and understand what you’re going through. By the end, you’ll know you’re not alone.

(Transcript Available Below)

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About The Not Crazy podcast Hosts

Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book, Mental Illness is an Asshole and other Observations, available from Amazon; signed copies are also available directly from Gabe Howard. To learn more, please visit his website, gabehoward.com.

 

 

 

 

Lisa is the producer of the Psych Central podcast, Not Crazy. She is the recipient of The National Alliance on Mental Illness’s “Above and Beyond” award, has worked extensively with the Ohio Peer Supporter Certification program, and is a workplace suicide prevention trainer. Lisa has battled depression her entire life and has worked alongside Gabe in mental health advocacy for over a decade. She lives in Columbus, Ohio, with her husband; enjoys international travel; and orders 12 pairs of shoes online, picks the best one, and sends the other 11 back.

 

 


Computer Generated Transcript for “Depression TipsEpisode

Editor’s NotePlease be mindful that this transcript has been computer generated and therefore may contain inaccuracies and grammar errors. Thank you.

Lisa: You’re listening to Not Crazy, a Psych Central podcast hosted by my ex-husband, who has bipolar disorder. Together, we created the mental health podcast for people who hate mental health podcasts.

Gabe: Hey, everyone, and welcome to this week’s episode of the Not Crazy podcast. My name is Gabe Howard and I am your host. But with me, as always, is the great Lisa Kiner.

Lisa: Oh, thank you, Gabe. And

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The sequence of hormonal therapy and radiation affects outcomes in men treated for prostate cancer – Harvard Health Blog

A common treatment for men with intermediate-risk prostate cancer is to combine radiation with drugs that block testosterone — a hormone that makes the tumors grow faster. (This type of treatment is also called androgen deprivation therapy, or ADT).

New research is suggesting the sequence of these treatments may be crucially important.

Dr. Dan Spratt, a professor of radiation oncology at the University of Michigan, led the research. He and his colleagues pooled data from two previously published clinical trials (here and here). Taken together, the studies enrolled just over 1,000 men who had been randomly assigned to one of two groups:

  • hormonal therapy given before radiation (followed in all cases by both treatments given together), or
  • hormonal therapy that started either concurrently with radiation and then continued after it was finished, or that started only after the radiation treatments were completed.

By themselves, the individual studies didn’t show a significant difference in outcomes after an average follow-up of nearly 15 years. But by pooling the data, Spratt’s team produced a dataset with enough statistical power to show that men who started on hormonal therapy either during or after radiation did significantly better in all respects: compared to the men who were treated with hormone therapy first, they had lesser odds of experiencing a rise in prostate-specific antigen levels (suggesting the cancer might be returning); they lived longer without a progression of their disease; and they were less likely to have cancer spread to other parts of the body. The results also suggested they had a lower risk of actually dying from prostate cancer, although this particular finding wasn’t statistically significant.

Researchers have already devoted a lot of attention to how long hormonal therapy should last when it’s given with radiation. This is now the first study to

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